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Foundations Pumping Cash Into Research on Diseases

Vertex acquired Aurora for about $600 million in stock in 2001.

The Cambridge, Mass.-based biotech company, best known for its HIV treatment Lexiva licensed to GlaxoSmithKline, employs about 150 people in San Diego, where it conducts cystic fibrosis research.

These groups are, in a way, pointing us toward finding a particular disease target, Negulescu said. In a way, we see it as where personalized medicine is going.

Vertex has two drug candidates focused on treating cystic fibrosis, a genetic disease that results from the inheritance of a defective gene.

Its drug candidates work by targeting a certain defective protein responsible for the progression of cystic fibrosis.

We actually knew about the gene defect for years but nobody had been working on trying to commercialize that defect, Negulescu said.


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J Kooman from Canada writes:

Jean-Pierre De Montigny from Montreal, Canada writes: I don't know why people complain so much about a fee of $10 per month. It is peanuts for the value. You will go out one night and spend a multiple of this for beer.
Interest rate on credit card? There is no charge if you pay your balance. If not, get a loan instead!

Your joking right? President's Choice Financial does not charge anything
for writing checks or paying bills and they have a higher savings interest rates. The only catch is you have to bank online or use CIBC ABMs Posted 29/02/08 at 12:01 PM EST | Alert an Editor | Link to Comment .


FCCJ Employee Accused Of Taking $102,000

JACKSONVILLE, Fla. -- An executive assistant at Florida Junior College at Jacksonville is accused of embezzling $102,000 from the college in a scheme involving a college credit card.

Cheryl Chesser, an employee of the college for 13 years, had stolen the money over the past five years, according to police.

"This was a very, very sophisticated embezzlement scheme," FCCJ President Steven Wallace said. .


Sunni Forces Losing Patience With U.S.

Since Feb. 8, thousands of fighters in restive Diyala province have left their posts in order to pressure the government and its American backers to replace the province's Shiite police chief. On Wednesday, their leaders warned that they would disband completely if their demands were not met. In Babil province, south of Baghdad, fighters have refused to man their checkpoints after U.S. soldiers killed several comrades in mid-February in circumstances that remain in dispute.

Some force leaders and ground commanders also reject a U.S.-initiated plan that they say offers too few Sunni fighters the opportunity to join Iraq's army and police, and warn that low salaries and late payments are pushing experienced members to quit.

The predominantly Sunni Awakening forces, referred to by the U.S.


Consumer Smarts: Vehicle warranty notice may mislead

The factory warranty on your vehicle is set to expire, it warns. This is your "final notice." You must call within 72 hours to renew.

Consumers everywhere -- even those who don't own cars -- have been flooded with such mailings and phone calls in recent months, and attorneys general in several states, including Washington, are warning consumers to beware. Many of the solicitations target seniors, pressuring them to buy expensive service contracts.

Q: What should I do about these extended warranty notices?

A: "Don't take the information on face value," urged Assistant Attorney General Mary Lobdell in a recent consumer alert. "These notices usually aren't from your manufacturer or dealer; they're ads from businesses that want to sell you an optional, pricey plan to cover future repairs."

Extended auto warranties, or vehicle service contracts, may be unnecessary and very expensive, costing $1,000 or more.


Whopping rumor slams into Microhoo

Jerry Yang, who founded the internet giant, has been vocal about a new strategy for Yahoo since he resumed control of the company last year. Earlier this week, two pieces of Yang's strategy became illuminated as he announced plans to let publishers make changes in Yahoo's search results while giving users a voice in determining the content of Yahoo's homepage.

Add to Yang's news the continuing rumors that Yahoo is in talks with News Corp. (deemed a long shot) and it's not clear that Microsoft and Yahoo are any closer to striking a deal.

Meanwhile, a second -- and perhaps more peculiar -- rumor has surfaced at TechCrunch where the blog is reporting that Google is planning to buy a minor stake in Yahoo to drive up the stock price and disrupt Microsoft's bid to buy the company.


Your Comments : Voreqe: Election still on

But of course guidelines set to have any thief, beggar man , fijian chief contest the elections.

28 days & 2 hrs agoSuggest removalPermalink

ex Fiji tourist of Australia says… "The military council feels strongly that convicted people should not stand for elections," explains army Legal Director Colonel Mohammed Aziz.

I wonder if he has discussed this with chaudrhy, the convicted deadly driver.

28 days & 2 hrs agoSuggest removalPermalink

Semi Meo of Australia says… Most of us woke up this morning with a glitter of HOPE beckoning us in the horizon...hope that Mr. Bainimarama and his Interim Government may just keep the Election 03 '09 promise!!

As a reciprocal act of goodwill for the common good, may be, it is time for Mr.


OQO e2 ultramobile PC with HSDPA review

It's designed to generate iPod-like love and envy, from the plain black box it arrives in, to the sturdy matt black aluminium case and luxurious 5in screen, which has a native resolution of 800 x 480.

The OQO e2 has the minimum of slots and buttons, and several very nice touches. Four white LEDs on the battery indicate the charge level when pressed, and flash during charging to indicate the current level of charge. There is also a thicker battery that lasts longer than the pretty-accurate quoted three hours of the normal battery.

Other items on the sides include a docking/power connector, HDMI connector (it can drive an external screen at up at 1,920x1,200), a headphone socket, a single USB slot and a slot for a Kensington lock.

The OQO e2's screen slides to one side to reveal a keyboard which makes good use of multiple functions on each key - but is not big enough for touch typing.


Letters to the Editor (March 4)

I am proud that Fidel Castro has stepped down on his own terms, gradually preparing his people, and the world, for others to take leadership, after surviving hundreds of attacks by U.S.My family in Cuba is divided on the revolution. But they all have affection for Fidel after so many years and support Hugo Chavez and are proud to be Cubans.Also, they all complain about the prices, and the economy. They all see the U.S. blockade as cruel, inhuman and ineffective.Cubans are like any "family" with differences and squabbles, but defend each other when attacked.Media reports the brokenness of Cuban buildings, lack of paint, sparsely equipped stores as a shortcoming of the Cuban government. Readers should know the U.S. not only blocks U.S. companies from trading with Cuba, but since passage of the 1996 Helms-Burton Act has held any non-U.S.


Inside Bush’s Brain: A Depression? ‘Bring It On’

This transcript appeared on my computer. It can't be verified, but it sounds right.

POTUS is speaking.

“My dad was right about Voodoo economics. Remember when he said that? I should have listened. Now they're putting that voodoo on me.

And he was also right about another thing: You never know who you can trust especially on this economy thing. That's what brought him down, not Bill Clinton.

Look at all we did for business. We gave them just about everything they wanted and now I find out they have been stealing from us, from us, damn it, in Iraq and, yes, here in the homeland.

And it's the finance guys that's have been doing most of it. I should have listened to Laura. She knew. I heard that Jesse Jackson is marching on Wall Street.


 
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